What Julian Rayner did with his prize money…
I work on malaria, and specifically how the parasites that cause malaria recognise and get inside our red blood cells. Malaria parasites have incredibly complicated life cycles, passing back and forth between humans and mosquitoes, but it is when they infect our red blood cells that they cause all the symptoms of malaria, including death – nearly a million children die from malaria every year. Our idea is that if we understand how they invade our red blood cells, we can come up with vaccines or drugs to try to block invasion, and so prevent malaria infection. The actual process of invasion is fascinating – it is literally one cell forcing it’s way inside another, with the parasite almost dragging the surface of the red blood cell around itself until it winds up inside, where it is protected from the human immune system and surrounded by lovely haemoglobin. We use … Continue reading